1. Dwight Freeney and Robert Mathis tee off. The Colts' defensive ends have combined for 18 sacks this season. Ravens offensive tackles Jared Gaither and Michael Oher can't let them get to Joe Flacco, who is dealing with knee and foot problems.
2. Reggie Wayne continues his hot streak. In the past three games, the Indianapolis wide receiver has averaged 10 catches and 112.3 receiving yards. The Ravens have allowed only two wide receivers (San Diego's Vincent Jackson and Minnesota's Sidney Rice) to record 100-yard receiving games this season.