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1 Dose 'Better Than None'

Officials Say Children Benefit Despite 2-dose H1n1 Vaccine Delay

October 24, 2009|By Meredith Cohn and Kelly Brewington , meredith.cohn@baltsun.com and Kelly.Brewington@baltsun.com

Because of slow production of the swine flu vaccine, public health officials aren't sure how fast Baltimore-area children will be able to get the two doses recommended for protection against the virus.

That's a concern because early monitoring shows that children are being hospitalized and dying from the H1N1 flu at higher rates than from a standard seasonal flu. And Friday, a top U.S. health official called the H1N1 flu "a young person's disease."

Still, experts recommend that children be vaccinated - even if a second dose cannot be scheduled.

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"If I had a child less than 10 years of age, I would absolutely give a child one dose. I think one is better than none," said Dr. Karen L. Kotloff, a professor of pediatrics at the University of Maryland School of Medicine.

Early studies of the swine flu vaccine show that children younger than 10 gain more protection from the virus when they receive two doses about three weeks apart. But supplies are coming slowly from the federal government, so local health departments and doctors have been concentrating on getting children and others their first doses.

The officials say even one dose will help children build antibodies in eight to 10 days. And they say there will be enough vaccine for round two, but no one can say exactly when. Providers are advising parents to mark their calendar and seek a second vaccination for children when and wherever they can: a school, a public clinic, a pediatrician's office or a retail outlet.

"At this point we plan to go back and give booster shots to the kids in school, unless we find there is not the need because they got the second dose somewhere else," said Dr. Peter L. Beilenson, Howard County's health officer.

Advice from the U.S. Centers for Disease Control and Prevention is based on preliminary results of trials conducted by the University of Maryland School of Medicine and other academic sites that measured antibody levels after vaccination.

A more definitive recommendation will come as soon as next week, when results are expected to be available from children given the vaccine 21 days before, rather than just eight days, which was the basis for the preliminary results, said Kotloff, who is leading the trials at the school's Center for Vaccine Development.

Kotloff says she thinks the recommendation for two doses of the H1N1 vaccine won't change - that's the same for children who get seasonal flu vaccine for the first time. Their immune systems have never been exposed to this new flu and so they do not have any protection against it.

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