The news was much better for No. 9 Johns Hopkins (9-4), No. 11 UMBC (12-3) and No. 12 Navy (11-4).
The Blue Jays earned the eighth seed and will play host to Brown (12-3) at noon Saturday. The Bears, who are making their first appearance in the tournament since 1997, are 1-9 all time against Johns Hopkins.
The Retrievers, who captured their third America East tournament crown in four years, will play at No. 6 seed North Carolina at 2:30 p.m. Saturday. The No. 8 Tar Heels (11-5) lost to Duke in the ACC tournament final last month.
The Midshipmen, the Patriot League tournament champions for the fifth time in six years, will play at third seed Duke at 7:30 p.m. Saturday. The Blue Devils (13-3) have captured three consecutive ACC tournament crowns and are on a seven-game winning streak that includes two victories over Virginia.
Despite those two losses to Duke after opening the season with 10 straight victories, the Cavaliers earned the top seed in the tournament and will welcome Villanova (11-5), the Colonial Athletic Association tournament champion, at 2:30 p.m. Sunday.
Reigning national champion Syracuse (11-2) earned the No. 2 seed and will play host to Siena (12-5), the Metro Atlantic Athletic Conference tournament champion, which will be making its first appearance in the NCAA tournament.
Baltimore Sun columnist Mike Preston contributed to this article.