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Screening not found to limit MRSA

Wards that test for `superbug' no better off than nontesters

March 12, 2008|By Dennis O'Brien , Sun reporter

Less than a month after the Maryland General Assembly rejected a bill that would have required hospitals to test incoming patients for the dangerous MRSA bacterium, researchers in Switzerland are reporting that screening doesn't reduce MRSA infections.

Researchers found that MRSA infection rates in wards where patients were pre-screened for the superbug were no different from infection rates in areas without screening, according to an article in today's Journal of the American Medical Association.

"It's just not very helpful," said Dr. Stephan Harbarth, the epidemiologist who led the study at the University of Geneva Hospitals.

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Harbarth examined MRSA infection rates among 21,754 patients treated in 12 surgical wards. His researchers tested incoming patients in half the wards for nine months and then switched testing to the other half for nine months.

Screening on admission identified 515 patients with MRSA - including 337 who would have otherwise been missed, according to the study. Infected patients were isolated, treated by personnel wearing gowns and gloves, cleaned with antimicrobials and given medications adjusted for the infection.

But the researchers found that only 93 additional patients developed MRSA while in wards where screening was conducted, compared with 76 in nonscreened wards - a difference they consider insignificant.

"There was not even the slightest trend toward reduction of MRSA infections in the screening wards," Harbarth said.

Harbarth recommends screening only in areas where the risk is highest: intensive care, critical care and cardiovascular surgical units.

Critics said the duration and scope of the study were too limited. Because patients in some wards weren't screened, MRSA could survive to be spread by hospital personnel, they said.

MRSA, or Methicillin-resistant Staphylococcus aureus, is a bacterium that can live harmlessly in the skin or nose but will attack wounds and cause life-threatening infections, including pneumonia and blood poisoning, when someone is hospitalized. Over the years, it has evolved into a superbug that resists most common antibiotics.

The federal Centers for Disease Control and Prevention estimates that MRSA caused 18,000 deaths in 2005. Last June, a study by the Association for Professionals in Infection Control and Epidemiology (APIC) found MRSA in 46 out of every 1,000 hospital patients.

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