Indianapolis (2-3) at Kansas City (1-5)
Time: 8:30, ESPN.
Line: Colts by 3.
Outlook: Both teams will be trying to end a three-game losing streak. The Colts have been blown out twice by New England this season, and their beleaguered defense gave up 385 yards in Sunday's 38-17 loss to the Patriots. The Chiefs, off to their worst start since 1988, when they were 1-8-1, haven't fared well vs. Indianapolis, losing the past five meetings. One of their few bright spots has been ex-Ravens RB Priest Holmes (475 yards, 5.3 per carry).